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Leaves and fruits preparations of pistacia lentiscus l.: A review on the ethnopharmacological uses and implications in inflammation and infection
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SYSNO ASEP 0546747 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Leaves and fruits preparations of pistacia lentiscus l.: A review on the ethnopharmacological uses and implications in inflammation and infection Tvůrce(i) Milia, E. (IT)
Bullitta, S. M. (IT)
Mastandrea, G. (IT)
Szotáková, B. (CZ)
Schoubben, A. (IT)
Langhansová, Lenka (UEB-Q) RID, ORCID
Quartu, M. (IT)
Bortone, A. (IT)
Eick, S. (CH)Celkový počet autorů 9 Číslo článku 425 Zdroj.dok. Antibiotics (Basel). - : MDPI - ISSN 2079-6382
Roč. 10, č. 4 (2021)Poč.str. 21 s. Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova Essential oils ; Ethanol extracts ; Mediterranean plants ; Natural anti-inflammatory ; Natural antimicrobials ; Pharmaceutical plants ; Polyphenols ; Terpenoids ; Water extracts Obor OECD Plant sciences, botany Způsob publikování Open access Institucionální podpora UEB-Q - RVO:61389030 UT WOS 000642694000001 EID SCOPUS 85104600564 DOI 10.3390/antibiotics10040425 Anotace There is an increasing interest in revisiting plants for drug discovery, proving scientifically their role as remedies. The aim of this review was to give an overview of the ethnopharmacological uses of Pistacia lentiscus L. (PlL) leaves and fruits, expanding the search for the scientific discovery of their chemistry, anti-inflammatory, antioxidative and antimicrobial activities. PlL is a wild-growing shrub rich in terpenoids and polyphenols, the oil and extracts of which have been widely used against inflammation and infections, and as wound healing agents. The more recurrent components in PlL essential oil (EO) are represented by α-pinene, terpinene, caryophyllene, limonene and myrcene, with high variability in concentration depending on the Mediterranean country. The anti-inflammatory activity of the oil mainly occurs due to the inhibition of pro-inflammatory cytokines and the arachidonic acid cascade. Interestingly, the capacity against COX-2 and LOX indicates PlL EO as a dual inhibitory compound. The high content of polyphenols enriching the extracts provide explanations for the known biological properties of the plant. The protective effect against reactive oxygen species is of wide interest. In particular, their anthocyanins content greatly clarifies their antioxidative capacity. Further, the antimicrobial activity of PlL oil and extracts includes the inhibition of Staphylococcus aureus, Escherichia coli, periodontal bacteria and Candida spp. In conclusion, the relevant scientific properties indicate PlL as a nutraceutical and also as a therapeutic agent against a wide range of diseases based on inflammation and infections. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2022 Elektronická adresa http://doi.org/10.3390/antibiotics10040425
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