Počet záznamů: 1
pH-responsive and antibacterial properties of self-assembled multilayer films based on chitosan and tannic acid
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SYSNO ASEP 0518031 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název pH-responsive and antibacterial properties of self-assembled multilayer films based on chitosan and tannic acid Tvůrce(i) Kumorek, Marta M. (UMCH-V) RID
Minisy, Islam M. (UMCH-V) RID, ORCID
Krunclová, Tereza (UMCH-V) ORCID
Voršiláková, Marta (UMCH-V)
Venclíková, Kristýna (UMCH-V) RID
Mázl Chánová, Eliška (UMCH-V) RID
Janoušková, Olga (UMCH-V) RID, SAI, ORCID
Kubies, Dana (UMCH-V) RID, ORCIDČíslo článku 110493 Zdroj.dok. Materials Science & Engineering C-Materials for Biological Applications. - : Elsevier - ISSN 0928-4931
Roč. 109, April (2020), s. 1-13Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova tannic acid ; chitosan ; layer-by-layer Vědní obor RIV CD - Makromolekulární chemie Obor OECD Polymer science CEP ED1.1.00/02.0109 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy LQ1604 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy NV16-28254A GA MZd - Ministerstvo zdravotnictví Způsob publikování Omezený přístup Institucionální podpora UMCH-V - RVO:61389013 UT WOS 000527394600015 EID SCOPUS 85076174234 DOI 10.1016/j.msec.2019.110493 Anotace Polyelectrolyte layer-by-layer (LbL) films that disintegrate under physiological conditions are intensively studied as coatings to enable the release of bioactive components. Herein, we report on the interactions and pH-stability of LbL films composed of chitosan (CH) or N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (CMCH) and tannic acid (TA), employed to guarantee the film disintegration. The self-assembly of TA with CH and CMCH at pH 5 and with CMCH at pH 7.4 were proven by turbidimetric, surface plasmon resonance and UV–Vis analyses. The LbL films exhibited pH-dependent properties. CMCH/TA films prepared at pH 7.4 showed exponential growth as well as a higher layer thickness and surface roughness, whereas films prepared at pH 5 grew linearly and were smoother. The film stability varied with the pH used for film assembly. CH/TA films assembled at pH 5 were unstable at pH 8.5, whereas CMCH/TA films assembled at pH 7.4 disintegrated at pH 4. All films exhibited a similar disassembly at pH 7.4. The coatings reduced the adhesion of E. coli and S. aureus by approximately 80%. CMCH-terminated CMCH/TA films were more resistant to bacterial adhesion, whereas CH-terminated CH/TA films demonstrated stronger killing activity. The prepared pH-triggered decomposable LbL films could be used as degradable coatings that allow the release of therapeutics for biomedical applications and also prevent bacterial adhesion. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2021 Elektronická adresa https://www.sciencedirect.com/science/article/pii/S0928493119303339?via%3Dihub
Počet záznamů: 1