Počet záznamů: 1
Methodologic recommendations and possible interpretations of video‐EEG recordings in immature rodents used as experimental controls: A TASK1‐WG2 report of the ILAE/AES Joint Translational Task Force
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SYSNO ASEP 0498675 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Ostatní články Název Methodologic recommendations and possible interpretations of video‐EEG recordings in immature rodents used as experimental controls: A TASK1‐WG2 report of the ILAE/AES Joint Translational Task Force Tvůrce(i) Akman, O. (TR)
Raol, Y. H. (US)
Auvin, S. (FR)
Cortez, M. A. (CA)
Kubová, Hana (FGU-C) RID, ORCID
de Curtis, M. (IT)
Ikeda, A. (JP)
Dudek, F. E. (US)
Galanopoulou, A. S. (US)Zdroj.dok. Epilepsia Open. - : Wiley
Roč. 3, č. 4 (2018), s. 437-459Poč.str. 23 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova minimum standards ; rat ; mouse ; vEEG ; ontogeny ; postnatal ; stereotaxic ; anesthesia ; cortical ; subcortical Vědní obor RIV FH - Neurologie, neurochirurgie, neurovědy Obor OECD Neurosciences (including psychophysiology CEP GA16-04726S GA ČR - Grantová agentura ČR LH15025 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora FGU-C - RVO:67985823 DOI 10.1002/epi4.12262 Anotace The use of immature rodents to study physiologic aspects of cortical development requires high‐quality recordings electroencephalography (EEG) with simultaneous video recording (vEEG) of behavior. Normative developmental vEEG data in control animals are fundamental for the study of abnormal background activity in animal models of seizures or other neurologic disorders. Electrical recordings from immature, freely behaving rodents can be particularly difficult because of the small size of immature rodents, their thin and soft skull, interference with the recording apparatus by the dam, and other technical challenges. In this report of the TASK1 Working Group 2 (WG2) of the International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force, we provide suggestions that aim to optimize future vEEG recordings from immature rodents, as well as their interpretation. We focus on recordings from immature rodents younger than 30 days old used as experimental controls, because the quality and correct interpretation of such recordings is important when interpreting the vEEG results of animals serving as models of neurologic disorders. We discuss the technical aspects of such recordings and compare tethered versus wireless approaches. We also summarize the appearance of common artifacts and various patterns of electrical activity seen in young rodents used as controls as a function of behavioral state, age, and (where known) sex and strain. The information herein will hopefully help improve the methodology of vEEG recordings from immature rodents and may lead to results and interpretations that are more consistent across studies from different laboratories. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2019
Počet záznamů: 1