Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches

MCINTYRE, P. J., COLLINS, P. M., VRZAL, Lukáš, BIRCHALL, K., ARNOLD, L. H., MPAMHANGA, C., COOMBS, P. J., BURGESS, S. G., RICHARDS, M. W., WINTER, A., VEVERKA, Václav, VON DELFT, F., MERRITT, A., BAYLISS, R. Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. ACS Chemical Biology. 2017, 12(11), 2906-2914. ISSN 1554-8929. E-ISSN 1554-8937. Dostupné z: doi: 10.1021/acschembio.7b00537