Počet záznamů: 1  

Is nucleus subthalamicus involved in thinking? Separation of conscious and subconscious cognition component in the subthalamic nucleus using P300 and MMN protocols

  1. 1.
    SYSNO ASEP0456445
    Druh ASEPA - Abstrakt
    Zařazení RIVZáznam nebyl označen do RIV
    Zařazení RIVNení vybrán druh dokumentu
    NázevIs nucleus subthalamicus involved in thinking? Separation of conscious and subconscious cognition component in the subthalamic nucleus using P300 and MMN protocols
    Tvůrce(i) Minks, E. (CZ)
    Jurák, Pavel (UPT-D) RID, ORCID, SAI
    Chládek, Jan (UPT-D) RID, ORCID, SAI
    Hummelová, Z. (CZ)
    Halámek, Josef (UPT-D) RID, ORCID, SAI
    Minksová, A. (CZ)
    Bareš, M. (CZ)
    Celkový počet autorů7
    Zdroj.dok.Clinical Neurophysiology. - : Elsevier - ISSN 1388-2457
    Roč. 126, č. 3 (2015), e49-e50
    Poč.str.1 s.
    Forma vydáníTištěná - P
    AkceCongress of the Czech and Slovak Society of Clinical Neurophysiology /61./
    Datum konání15.10.2015-18.10.2015
    Místo konáníOlomouc
    ZeměCZ - Česká republika
    Typ akceWRD
    Jazyk dok.eng - angličtina
    Země vyd.IE - Irsko
    Klíč. slovaoddball ; MMN ; P300 ; ERP ; EEG ; DBS ; STN ; conscious cognitive processes
    Vědní obor RIVBH - Optika, masery a lasery
    Institucionální podporaUPT-D - RVO:68081731
    AnotaceP300 wave is considered a correlate of cognitive process and an oddball paradigm is used for its recording. MMN (Mismatch negativity) is considered a correlation of automatic sensory memory on a subconscious level and also a reflection of subconscious primitive sensory intelligence. When the MMN is recorded the same protocol as P300 paradigm is used, only with the difference that the proband pays no attention to the stimuli. The aim of this study was to compare evoked potentials from the P300 paradigm against MMN paradigm, both recorded in the subthalamic nucleus (STN) and thus electrophysiologically isolate conscious cognition component in this structure. We included 3 patients with Parkinson´s disease and recorded the evoked potentials using protocols P300 and MMN during installation of DBS (Deep brain stimulation). The difference between evoked potentials of MMN and P300 protocols in latency of 200-400 ms suggests that STN is involved in conscious cognitive processes at the time of stimuli application. Thus the thinking at a given time is not a function of the brain cortex only. What component of the cognitive processes STN does represent cannot be exactly specified. Although oddball paradigm is very simple, during this paradigm the patient uses a variety of cognitive functions attention, executive function, working memory, calculation and proper level of motivation is necessary too.
    PracovištěÚstav přístrojové techniky
    KontaktMartina Šillerová, sillerova@ISIBrno.Cz, Tel.: 541 514 178
    Rok sběru2016
Počet záznamů: 1  

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