Počet záznamů: 1
Intracellular Delivery II: Fundamentals and Applications
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SYSNO ASEP 0441403 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine Tvůrce(i) Šlegerová, Jitka (UOCHB-X) RID, ORCID
Řehoř, Ivan (UOCHB-X) RID, ORCID
Havlík, Jan (UOCHB-X) RID
Raabová, Helena (UOCHB-X)
Muchová, Eva (UOCHB-X) RID
Cígler, Petr (UOCHB-X) RID, ORCIDCelkový počet autorů 6 Zdroj.dok. Intracellular Delivery II: Fundamentals and Applications. - Dordrecht : Springer, 2014 / Prokop A. ; Iwasaki Y. ; Harada A. - ISBN 978-94-017-8895-3 Rozsah stran s. 363-401 Poč.str. 39 s. Poč.str.knihy 479 Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova nanodiamond ; fluorescence ; nitrogen-vacancy center ; intracellular probe ; bioimaging ; biocompatibility Vědní obor RIV EI - Biotechnologie a bionika Institucionální podpora UOCHB-X - RVO:61388963 UT WOS 000344881200019 DOI 10.1007/978-94-017-8896-0_18 Anotace In recent years, diamond nanoparticles have received a great deal of attention due to their unique photophysical and biological properties. Nanodiamonds (NDs) show low toxicity and are considered to be a highly biocompatible carbon nanomaterial useful in a wide range of applications. Thanks to their ability to accommodate nitrogen-vacancy (N-V) color centers, NDs are a prime example of non-photobleachable fluorescent labels and nanosensors. Here, we present a survey of ND applications in biology and medicine with an emphasis on bioimaging. We focus on distinguishing the properties of detonation NDs and high-pressure high-temperature (HPHT) NDs and describing their physicochemical properties, structure and possible modifications by small molecules and biomolecules. We summarize and critically evaluate in vitro and in vivo data on ND toxicity and biocompatibility, cellular internalization, localization and targeting by surface-attached ligands. We discuss current achievements in bioimaging using fluorescent NDs and the potential of NDs in diagnostics and drug delivery. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2015
Počet záznamů: 1