Počet záznamů: 1
Immunochemical detection of oxidatively damaged DNA
- 1.0377754 - ÚEM 2013 RIV GB eng J - Článek v odborném periodiku
Rössner ml., Pavel - Šrám, Radim
Immunochemical detection of oxidatively damaged DNA.
Free Radical Research. Roč. 46, č. 4 (2012), s. 492-522. ISSN 1071-5762. E-ISSN 1029-2470
Grant CEP: GA MŽP(CZ) SP/1B3/50/07; GA MŠMT 2B08005; GA ČR GAP503/11/0084
Výzkumný záměr: CEZ:AV0Z50390703
Institucionální podpora: RVO:68378041
Klíčová slova: oxidative DNA damage * ELISA * immunohistochemistry
Kód oboru RIV: DN - Vliv životního prostředí na zdraví
Impakt faktor: 3.279, rok: 2012
Several methods have been developed to detect oxidatively damaged DNA. This review evaluates the studies dealing with the detection of 8-oxodG in humans, the most abundant oxidized nucleoside. Authors concentrated especially on studies which used enzyme linked immunosorbent assay and immunohistochemistry to detect 8-oxodG in humans, laboratory animals and in cell lines. Oxidative damage observed in these organisms resulted from disease, exposure to environmental pollutants of from in vitro treatment with various chemical and physical factors.
Trvalý link: http://hdl.handle.net/11104/0209834
Počet záznamů: 1