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Recent Advances in the Detection of Food Toxins Using Mass Spectrometry
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SYSNO ASEP 0580587 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Recent Advances in the Detection of Food Toxins Using Mass Spectrometry Tvůrce(i) Ahuja, V. (IN)
Singh, A. (IN)
Paul, D. (IN)
Dasgupta, D. (IN)
Urajová, Petra (MBU-M)
Gosh, Sounak (MBU-M)
Sing, Roshami (MBU-M)
Sahoo, Gobardhan (MBU-M)
Ewe, Daniela (MBU-M) ORCID
Saurav, Kumar (MBU-M) ORCIDZdroj.dok. Chemical Research in Toxicology - ISSN 0893-228X
Roč. 36, č. 12 (2023), s. 1834-1863Poč.str. 30 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova solid-phase extraction ; okadaic acid ; mycotoxin analysis ; shellfish toxins ; rapid detection ; lc-ms/ms ; icp-ms ; identification ; health ; ochratoxin Obor OECD Medicinal chemistry Způsob publikování Open access Institucionální podpora MBU-M - RVO:61388971 UT WOS 001127587500001 EID SCOPUS 85180109184 DOI 10.1021/acs.chemrestox.3c00241 Anotace Edibles are the only source of nutrients and energy for humans. However, ingredients of edibles have undergone many physicochemical changes during preparation and storage. Aging, hydrolysis, oxidation, and rancidity are some of the major changes that not only change the native flavor, texture, and taste of food but also destroy the nutritive value and jeopardize public health. The major reasons for the production of harmful metabolites, chemicals, and toxins are poor processing, inappropriate storage, and microbial spoilage, which are lethal to consumers. In addition, the emergence of new pollutants has intensified the need for advanced and rapid food analysis techniques to detect such toxins. The issue with the detection of toxins in food samples is the nonvolatile nature and absence of detectable chromophores, hence, normal conventional techniques need additional derivatization. Mass spectrometry (MS) offers high sensitivity, selectivity, and capability to handle complex mixtures, making it an ideal analytical technique for the identification and quantification of food toxins. Recent technological advancements, such as high-resolution MS and tandem mass spectrometry (MS/MS), have significantly improved sensitivity, enabling the detection of food toxins at ultralow levels. Moreover, the emergence of ambient ionization techniques has facilitated rapid in situ analysis of samples with lower time and resources. Despite numerous advantages, the widespread adoption of MS in routine food safety monitoring faces certain challenges such as instrument cost, complexity, data analysis, and standardization of methods. Nevertheless, the continuous advancements in MS-technology and its integration with complementary techniques hold promising prospects for revolutionizing food safety monitoring. This review discusses the application of MS in detecting various food toxins including mycotoxins, marine biotoxins, and plant-derived toxins. It also explores the implementation of untargeted approaches, such as metabolomics and proteomics, for the discovery of novel and emerging food toxins, enhancing our understanding of potential hazards in the food supply chain. Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2024 Elektronická adresa https://pubs.acs.org/doi/10.1021/acs.chemrestox.3c00241
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