Počet záznamů: 1
Comparative analysis of the midgut microbiota of two natural tick vectors of Rickettsia rickettsii
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SYSNO ASEP 0540933 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Comparative analysis of the midgut microbiota of two natural tick vectors of Rickettsia rickettsii Tvůrce(i) Pavanelo, D.B. (BR)
Schroder, N.C.H. (BR)
Pin Viso, N.D. (AR)
Martins, Larissa Almeida (BC-A) RID, ORCID
Malossi, C.D. (BR)
Galletti, M.F.B.M. (BR)
Labruna, M. B. (BR)
Daffre, S. (BR)
Farber, M. (AR)
Fogaca, A.C. (BR)Celkový počet autorů 10 Číslo článku 103606 Zdroj.dok. Developmental and Comparative Immunology. - : Elsevier - ISSN 0145-305X
Roč. 106, May 106 (2020)Poč.str. 5 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova amblyomma-aureolatum ; spotted-fever ; protease inhibitor ; cajennense ; infection ; symbiont ; disease ; Host-microbe interaction ; Microbiota ; Midgut ; Rickettsiae ; Tick ; Vector competence Vědní obor RIV EC - Imunologie Obor OECD Immunology Způsob publikování Omezený přístup Institucionální podpora BC-A - RVO:60077344 UT WOS 000517853000001 EID SCOPUS 85077375229 DOI 10.1016/j.dci.2019.103606 Anotace Although the ticks Amblyomma sculptum and Amblyomma aureolatum are important vectors of Rickettsia rickettsii, causative agent of the life-threatening Rocky Mountain spotted fever, A. aureolatum is considerably more susceptible to infection than A. sculptum. As the microbiota can interfere with the colonization of arthropod midgut (MG) by pathogens, in the current study we analyzed the MG microbiota of both tick species. Our results revealed that the MG of A. aureolatum harbors a prominent microbiota, while A. sculptum does not. Remarkably, a significant reduction of the bacterial load was recorded in R. rickettsii-infected A. aureolatum. In addition, the taxonomy analysis of the MG bacterial community of A. aureolatum revealed a dominance of the genus Francisella, suggesting an endosymbiosis. This study is the first step in getting insights into the mechanisms underlying the interactions among Amblyomma species, their microbiota and R. rickettsii. Additional studies to better understand these mechanisms are required and may help the development of novel alternatives to block rickettsial transmission. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2021 Elektronická adresa https://www.sciencedirect.com/science/article/pii/S0145305X19305178?via%3Dihub
Počet záznamů: 1