Počet záznamů: 1
Electrophoretically Deposited Layers of Octahedral Molybdenum Cluster Complexes: A Promising Coating for Mitigation of Pathogenic Bacterial Biofilms under Blue Light
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SYSNO ASEP 0535532 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Electrophoretically Deposited Layers of Octahedral Molybdenum Cluster Complexes: A Promising Coating for Mitigation of Pathogenic Bacterial Biofilms under Blue Light Tvůrce(i) Kirakci, Kaplan (UACH-T) SAI, RID, ORCID
Nguyen, T. K. N. (JP)
Grasset, F. (JP)
Uchikoshi, T. (JP)
Zelenka, J. (CZ)
Kubát, Pavel (UFCH-W) RID, ORCID, SAI
Ruml, T. (CZ)
Lang, Kamil (UACH-T) SAI, RID, ORCIDCelkový počet autorů 8 Zdroj.dok. ACS Applied Materials and Interfaces. - : American Chemical Society - ISSN 1944-8244
Roč. 12, č. 47 (2020), s. 52492-52499Poč.str. 8 s. Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova biofilm ; electrophoretic deposition ; luminescence ; molybdenum cluster complex ; phototoxicity ; singlet oxygen Vědní obor RIV CA - Anorganická chemie Obor OECD Inorganic and nuclear chemistry Vědní obor RIV – spolupráce Ústav fyzikální chemie J.Heyrovského - Fyzikální chemie a teoretická chemie CEP GA19-09721S GA ČR - Grantová agentura ČR Způsob publikování Omezený přístup Institucionální podpora UACH-T - RVO:61388980 ; UFCH-W - RVO:61388955 UT WOS 000595547400022 EID SCOPUS 85096535089 DOI https://doi.org/10.1021/acsami.0c19036 Anotace The fight against infective microorganisms is becoming a worldwide priority due to serious concerns about the rising numbers of drug-resistant pathogenic bacteria. In this context, the inactivation of pathogens by singlet oxygen, O2(1Δg), produced by photosensitizers upon light irradiation has become an attractive strategy to combat drug-resistant microbes. To achieve this goal, we electrophoretically deposited O2(1Δg)-photosensitizing octahedral molybdenum cluster complexes on indium-tin oxide-coated glass plates. This procedure led to the first example of molecular photosensitizer layers able to photoinactivate bacterial biofilms. We delineated the morphology, composition, luminescence, and singlet oxygen formation of these layers and correlated these features with their antibacterial activity. Clearly, continuous 460 nm light irradiation imparted the layers with strong antibacterial properties, and the activity of these layers inhibited the biofilm formation and eradicated mature biofilms of Gram-positive Staphylococcus aureus and Enterococcus faecalis, as well as, Gram-negative Pseudomonas aeruginosa and Escherichia coli bacterial strains. Overall, the microstructure-related oxygen diffusivity of the layers and the water stability of the complexes were the most critical parameters for the efficient and durable use. These photoactive layers are attractive for the design of antibacterial surfaces activated by visible light and include additional functionalities such as the conversion of harmful UV/blue light to red light or oxygen sensing. Pracoviště Ústav anorganické chemie Kontakt Jana Kroneislová, krone@iic.cas.cz, Tel.: 311 236 931 Rok sběru 2021 Elektronická adresa https://pubs.acs.org/doi/10.1021/acsami.0c19036
Počet záznamů: 1