Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools

0474398 - BTÚ 2018 RIV US eng J - Článek v odborném periodiku
Nováková, Zora - Foss, C. A. - Copeland, B. T. - Morath, V. - Baranová, Petra - Havlínová, Barbora - Skerra, A. - Pomper, M.G. - Bařinka, Cyril
Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools.
Prostate. Roč. 77, č. 7 (2017), s. 749-764. ISSN 0270-4137. E-ISSN 1097-0045
Grant CEP: GA ČR GAP301/12/1513; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institucionální podpora: RVO:86652036
Klíčová slova: monoclonal antibody * glutamate carboxypeptidase II * NAALADase
Obor OECD: Endocrinology and metabolism (including diabetes, hormones)
Impakt faktor: 3.347, rok: 2017

BACKGROUND. Prostate-specific membrane antigen (PSMA) is a validated target for the imaging and therapy of prostate cancer. Here, we report the detailed characterization of four novel murine monoclonal antibodies (mAbs) recognizing human PSMA as well as PSMA orthologs from different species.
Trvalý link: http://hdl.handle.net/11104/0271465