In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

LYNN, G. M., LAGA, Richard, DARRAH, P. A., ISHIZUKA, A. S., BALACI, A. J., DULCEY, A. E., PECHAR, Michal, POLA, Robert, GERNER, M. Y., YAMAMOTO, A., BUECHLER, C. R., QUINN, K. M., SMELKINSON, M. G., VANEK, O., CAWOOD, R., HILLS, T., VASALATIY, O., KASTENMÜLLER, K., FRANCICA, J. R., STUTTS, L., TOM, J. K., AH RYU, K., ESSER-KAHN, A. P., ETRYCH, Tomáš, FISHER, K. D., SEYMOUR, L. W., SEDER, R. A. In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nature Biotechnology. 2015, 33(11), 1201-1210. ISSN 1087-0156. E-ISSN 1546-1696. Dostupné z: doi: 10.1038/nbt.3371