Počet záznamů: 1
Phenotypic effects of CD3zeta targeting into glycosphingolipid-enriched membrane microdomains (GEMs) of T cells
- 1.0191079 - UMG-J 20000182 RIV US eng J - Článek v odborném periodiku
Cebecauer, Marek - Černý, Jan
Phenotypic effects of CD3zeta targeting into glycosphingolipid-enriched membrane microdomains (GEMs) of T cells.
Biochemical and Biophysical Research Communications. Roč. 271, č. 3 (2000), s. 589-595. ISSN 0006-291X. E-ISSN 1090-2104
Grant CEP: GA ČR GA204/99/0367; GA AV ČR IAA7052904; GA MŠMT VS97099; GA AV ČR KSK2038602
Výzkumný záměr: CEZ:AV0Z5052915
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 3.055, rok: 2000
A form of CD3-zeta chain was constructed which is constitutively expressed in signaling microdomains (GEMs) ofT-lymphocytes. Contrary to expectations, the modification of GEMs with this CD3-zeta (constitutively Tyr-phosphorylated) did not produce a spontaneously activated phenotype (IL-2 and CD69 production not observed).
Trvalý link: http://hdl.handle.net/11104/0086839
Počet záznamů: 1