Počet záznamů: 1
Structure-property correlation studies of cross-linked citric acid-based elastomers
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SYSNO ASEP 0567520 Druh ASEP J - Článek v odborném periodiku Zařazení RIV O - Ostatní Poddruh J Ostatní články Název Structure-property correlation studies of cross-linked citric acid-based elastomers Tvůrce(i) Koper, F. (PL)
Świergosz, T. (PL)
Zaba, A. (PL)
Flis, A. (PL)
Trávníčková, Martina (FGU-C) RID, ORCID, SAI
Bačáková, Lucie (FGU-C) RID, ORCID
Pamula, E. (PL)
Bogdal, D. (PL)
Kasprzyk, W. (PL)Zdroj.dok. Engineering of Biomaterials - ISSN 1429-7248
Roč. 24, č. 163 (2021), s. 45-45Poč.str. 1 s. Akce Conference Biomaterials in Medicine and Veterinary Medicine /30./ Datum konání 14.10.2021 - 17.10.2021 Místo konání Rytro Země PL - Polsko Typ akce EUR Jazyk dok. eng - angličtina Země vyd. PL - Polsko Klíč. slova elastomers ; biomaterials ; poly(alkylene citrate) (PAC) biomaterials Obor OECD Biomaterials (as related to medical implants, devices, sensors) CEP GA21-06065S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora FGU-C - RVO:67985823 Anotace In recent years, poly(alkylene citrate) (PAC) biomaterials have become one of the most promising biomaterials for the production of scaffolds for soft tissue engineering . Moreover, they were considered as components of numerous composites and copolymers studied in a wide range of possible medical applications. In terms of mechanical properties, PAC-based materials are similar to those of human tissues and can be readily tailored to specific needs thus providing the opportunity of being adopted to a variety of bioengineering applications. In addition, cell proliferation studies indicated their remarkable biocompatibility and absence of cytotoxicity, with a significant decrease in thrombogenicity. However, challenging structural characterization of PAC prepolymers has been reported in only a few reports despite the extensive published literature , with the majority of papers showing serious incoherencies in the discussion of the reported spectroscopic results. Hence, the main focus of this work was to optimize the composition and synthesis parameters of PAC polymers based on two diols: 1,6-hexanediol or 1,8-octanediol in two comonomer molar ratios, to obtain materials with defined structure and physicochemical properties. For evaluating their suitability as biomaterials, experiments were performed with adipose tissue-derived stem cells. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2023 Elektronická adresa http://www.biomaterials.pl/Issue-Special%20Issue%20163-2021,10425
Počet záznamů: 1