Počet záznamů: 1
How alternative splicing changes the properties of plant proteins
- 1.0565617 - ÚEB 2023 RIV GB eng J - Článek v odborném periodiku
Kashkan, Ivan - Timofeyenko, Ksenia - Růžička, Kamil
How alternative splicing changes the properties of plant proteins.
Quantitative Plant Biology. Roč. 3, Jul (2022), č. článku e14. E-ISSN 2632-8828
Grant CEP: GA MŠMT(CZ) EF16_019/0000738
Institucionální podpora: RVO:61389030
Klíčová slova: alternative splicing * competitive inhibition * feedback loop
Obor OECD: Biochemical research methods
Způsob publikování: Open access
https://doi.org/10.1017/qpb.2022.9
Most plant primary transcripts undergo alternative splicing (AS), and its impact on protein diversity is a subject of intensive investigation. Several studies have uncovered various mechanisms of how particular protein splice isoforms operate. However, the common principles behind the AS effects on protein function in plants have rarely been surveyed. Here, on the selected examples, we highlight diverse tissue expression patterns, subcellular localization, enzymatic activities, abilities to bind other molecules and other relevant features. We describe how the protein isoforms mutually interact to underline their intriguing roles in altering the functionality of protein complexes. Moreover, we also discuss the known cases when these interactions have been placed inside the autoregulatory loops. This review is particularly intended for plant cell and developmental biologists who would like to gain inspiration on how the splice variants encoded by their genes of interest may coordinately work.
Trvalý link: https://hdl.handle.net/11104/0337134
Název souboru Staženo Velikost Komentář Verze Přístup 2022_Kashkan_Quantitative Plant Biology_e14.pdf 2 573 KB Jiná povolen
Počet záznamů: 1