Phenotype, Immunological Reactivity and Cytokine Production Profile of Peyer`s Patch Cells from Mice Immunized Orally with Allogeneic Cells

0190946 - UMG-J 20000042 RIV CZ eng J - Článek v odborném periodiku
Frič, Jan - Krulová, Magdalena - Zajícová, Alena - Holáň, Vladimír
Phenotype, Immunological Reactivity and Cytokine Production Profile of Peyer`s Patch Cells from Mice Immunized Orally with Allogeneic Cells.
Folia Biologica. Roč. 46, č. 3 (2000), s. 119-125. ISSN 0015-5500. E-ISSN 0015-5500
Grant CEP: GA ČR GA310/99/0360; GA ČR GA310/97/1261; GA ČR GA310/99/D044; GA MZd IZ3964; GA MŠMT VS97099; GA MŠMT ME 300
Grant ostatní: NATO(BE) CRG.LG972853
Výzkumný záměr: CEZ:AV0Z5052915
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 0.351, rok: 2000

Changes in immunological reactivity of mice after oral administration of allogeneic cells have been studied. It wasshown that oral immunization specifically inhibits the immune system and that it is possible to demonstrate these changes already at the level of Peyer`s patch cells. Using the ELISA test and RT-PCR, increased production of Th1 cytokines has been shown. This immunization was demonstrated systemically by increased resistance to the growth of allogeneic tumors.
Trvalý link: http://hdl.handle.net/11104/0086708