Počet záznamů: 1
Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase
- 1.0142432 - FGU-C 20030028 RIV US eng J - Článek v odborném periodiku
Kubala, Martin - Teisinger, Jan - Ettrich, Rüdiger - Hofbauerová, Kateřina - Kopecký ml., Vladimír - Baumruk, V. - Krumscheid, R. - Plášek, J. - Schoner, W. - Amler, Evžen
Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.
Biochemistry. Roč. 42, č. 21 (2003), s. 6446-6452. ISSN 0006-2960
Grant CEP: GA ČR GA204/01/0254; GA ČR GA204/01/1001; GA ČR GA309/02/1479
Grant ostatní: GA-(CZ) CZE00/033
Výzkumný záměr: CEZ:AV0Z5011922; CEZ:MSM 123100001; CEZ:MSM 113100001; CEZ:MSM 113200001
Klíčová slova: sodium pump * ATP-binding site * TNP-ATP
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 3.922, rok: 2003
Site directed mutagenesis was used for introduction of point mutations in the H4-H5 loop of Na+/K+-ATPase. Influence of these mutations on the enzymes function was evaluated by fluorescence probe TNP-ATP and its competitive replacement by ATP. Eight amino acids were identified to form the ATP-binding site.
Trvalý link: http://hdl.handle.net/11104/0040135
Počet záznamů: 1