Počet záznamů: 1
Microreaction and membrane technologies for continuous single-enantiomer production: A review
- 1.
SYSNO ASEP 0545922 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Microreaction and membrane technologies for continuous single-enantiomer production: A review Tvůrce(i) Petrusová, Zuzana (UCHP-M) RID, ORCID, SAI
Slouka, Z. (CZ)
Vobecká, L. (CZ)
Polezhaev, Petr (UCHP-M) RID, ORCID, SAI
Hasal, P. (CZ)
Přibyl, M. (CZ)
Izák, Pavel (UCHP-M) RID, ORCID, SAIZdroj.dok. Catalysis Reviews-Science and Engineering. - : Taylor & Francis - ISSN 0161-4940
Roč. 65, č. 3 (2023), s. 773-821Poč.str. 49 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova mcrofluidics ; microreactor ; continuous flow synthesis Vědní obor RIV CI - Průmyslová chemie a chemické inženýrství Obor OECD Chemical process engineering CEP GA20-09980S GA ČR - Grantová agentura ČR Způsob publikování Open access Institucionální podpora UCHP-M - RVO:67985858 UT WOS 000702628000001 EID SCOPUS 85115871950 DOI 10.1080/01614940.2021.1977009 Anotace Microreaction and membrane technologies offer optimal conditions for controlling enantiomer synthesis and purification processes in continuous production, with numerous advantages over batch manufacturing. One of the many forces driving the development of such technologies for the production of single optical isomers is the need for enantiomerically pure pharmaceutical drugs because enantiomers may display opposite therapeutic effects or different treatment efficacies and side effects. Yet, despite advances in asymmetric synthesis and separation techniques, preparing enantiomerically pure compounds remains a challenging task. Here, we review the progress in microfluidics and membrane chiral separation over the last two decades. In addition to describing and critically assessing the state of the art in both disciplines, we provide an overview of their beneficial properties and characteristics for developing technologies toward producing enantiomerically pure compounds. Concomitantly, we evaluate efforts to integrate synthesis and membrane separation into a microfluidic platform and pinpoint the limiting factors that must be overcome before these platforms can be fully deployed in the industry. Pracoviště Ústav chemických procesů Kontakt Eva Jirsová, jirsova@icpf.cas.cz, Tel.: 220 390 227 Rok sběru 2024 Elektronická adresa https://www.tandfonline.com/doi/full/10.1080/01614940.2021.1977009
Počet záznamů: 1