Počet záznamů: 1  

Effect of Ni ion release on the cells in contact with NiTi alloys

  1. 1.
    0534086 - ÚFM 2021 RIV DE eng J - Článek v odborném periodiku
    Veverková, J. - Bártková, Denisa - Weiser, Adam - Dlouhý, Antonín - Babula, P. - Štěpka, P. - Goldbergová, M. P.
    Effect of Ni ion release on the cells in contact with NiTi alloys.
    Environmental Science and Pollution Research. ROČ. 27, č. 8 (2020), s. 7934-7942. ISSN 0944-1344. E-ISSN 1614-7499
    Grant CEP: GA ČR(CZ) GA15-16336S
    Institucionální podpora: RVO:68081723
    Klíčová slova: Nitinol * Cell * Biocompatibility * Biomaterial * Hydrogen modification
    Obor OECD: Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
    Impakt faktor: 4.223, rok: 2020
    Způsob publikování: Omezený přístup
    https://link.springer.com/article/10.1007/s11356-019-07506-8

    Nickel-titanium alloys have been used in medical applications for several years, however, biocompatibility of the material
    remains controversial. In the present study, the human umbilical vein endothelial cells (HUVEC) were cultured in contact with
    the nitinol used in two different heat treatment surface modifications—helium and hydrogen. The amount of Ni ions released
    from these alloys in contact with HUVEC was measured in media and in the cells by ICP-MS. An increased release of Ni ions
    was detected in He alloy compared with H2 alloy modification with an elevation with the metal exposition duration (24 h vs.
    72 h). The cells contained the Ni ions in both selected alloy modifications with the lower levels in H2 alloys. To evaluate the
    potential of multiple metal applications, similar values were observed in media and in cell suspension for all surface modification
    combinations. The model analysis of effect of metal ion release on distant cells in the body showed that the concentration is
    interestingly similar to concentrations in cells in direct contact with the metal alloy. The cells are able to regulate the concentration
    of Ni ions within the cell. According to our best knowledge, the study for the first time describes the presence of Ni ions released
    from nitinol directly in the cells. In the case of the H2 modification, the lowest levels of Ni ions were detected both in medium and
    in the cells, which likely increases the biocompatibility of the nitinol alloy.
    Trvalý link: http://hdl.handle.net/11104/0312304

     
     
Počet záznamů: 1  

  Tyto stránky využívají soubory cookies, které usnadňují jejich prohlížení. Další informace o tom jak používáme cookies.