Počet záznamů: 1
Transcriptome, proteome and draft genome of Euglena gracilis
- 1.
SYSNO ASEP 0519415 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Transcriptome, proteome and draft genome of Euglena gracilis Tvůrce(i) Ebenezer, N.D. (GB)
Zoltner, M. (GB)
Burrell, A. (GB)
Nenarokova, Anna (BC-A) RID, ORCID
Vanclová-Novák, A.M.G. (CZ)
Prasad, B. (DE)
Soukal, P. (CZ)
Santana-Molina, C. (ES)
O'Neill, E. (GB)
Nankissoor, N.N. (CA)
Vadakedath, N. (DE)
Daiker, V. (DE)
Obado, S. (US)
Silva-Pereira, S. (GB)
Jackson, A.P. (GB)
Devos, D.P. (ES)
Lukeš, Julius (BC-A) RID, ORCID
Lebert, M. (DE)
Vaughan, S. (GB)
Hampl, V. (CZ)
Carrington, M. (GB)
Ginger, M. L. (GB)
Dacks, J.B. (CA)
Kelly, S. (GB)
Field, Mark Christian (BC-A) ORCIDCelkový počet autorů 25 Číslo článku 11 Zdroj.dok. BMC BIOLOGY. - : BioMed Central
Roč. 17, FEB 7 2019 (2019)Poč.str. 23 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova trypanosoma-brucei ; gene-expression ; signal-transduction ; likely common ; tubulin genes ; beta-tubulin ; sequence ; evolution ; biosynthesis ; annotation ; Euglena gracilis ; Transcriptome ; Cellular evolution ; Plastid ; Horizontal gene transfer ; Gene architecture ; Splicing ; Secondary endosymbiosis ; Excavata Vědní obor RIV EH - Ekologie - společenstva Obor OECD Ecology CEP LL1601 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy EF16_019/0000759 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora BC-A - RVO:60077344 UT WOS 000458128000001 EID SCOPUS 85061200138 DOI 10.1186/s12915-019-0626-8 Anotace BackgroundPhotosynthetic euglenids are major contributors to fresh water ecosystems. Euglena gracilis in particular has noted metabolic flexibility, reflected by an ability to thrive in a range of harsh environments. E. gracilis has been a popular model organism and of considerable biotechnological interest, but the absence of a gene catalogue has hampered both basic research and translational efforts.ResultsWe report a detailed transcriptome and partial genome for E. gracilis Z1. The nuclear genome is estimated to be around 500Mb in size, and the transcriptome encodes over 36,000 proteins and the genome possesses less than 1% coding sequence. Annotation of coding sequences indicates a highly sophisticated endomembrane system, RNA processing mechanisms and nuclear genome contributions from several photosynthetic lineages. Multiple gene families, including likely signal transduction components, have been massively expanded. Alterations in protein abundance are controlled post-transcriptionally between light and dark conditions, surprisingly similar to trypanosomatids.ConclusionsOur data provide evidence that a range of photosynthetic eukaryotes contributed to the Euglena nuclear genome, evidence in support of the shopping bag' hypothesis for plastid acquisition. We also suggest that euglenids possess unique regulatory mechanisms for achieving extreme adaptability, through mechanisms of paralog expansion and gene acquisition. Pracoviště Biologické centrum (od r. 2006) Kontakt Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Rok sběru 2020 Elektronická adresa https://bmcbiol.biomedcentral.com/track/pdf/10.1186/s12915-019-0626-8
Počet záznamů: 1