Počet záznamů: 1  

Host subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)

  1. 1.
    SYSNO ASEP0492343
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JČlánek ve WOS
    NázevHost subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)
    Tvůrce(i) Čížková, Dagmar (UBO-W) RID, SAI, ORCID
    Baird, Stuart J. E. (UBO-W) RID, ORCID, SAI
    Těšíková, Jana (UBO-W) SAI, ORCID
    Voigt, S. (DE)
    Ďureje, Ľudovít (UBO-W) RID, SAI, SAI
    Piálek, Jaroslav (UBO-W) RID, ORCID, SAI
    Goüy de Bellocq, Joëlle (UBO-W) RID, ORCID, SAI, SAI
    Celkový počet autorů7
    Zdroj.dok.Virology. - : Elsevier - ISSN 0042-6822
    Roč. 521, August (2018), s. 92-98
    Poč.str.7 s.
    Jazyk dok.eng - angličtina
    Země vyd.US - Spojené státy americké
    Klíč. slovaMurine cytomegalovirus ; House mouse ; Mus musculus musculus ; Host-specificity ; Introgression ; Hybrid zone
    Vědní obor RIVEE - Mikrobiologie, virologie
    Obor OECDVirology
    CEPGA14-35009S GA ČR - Grantová agentura ČR
    Institucionální podporaUBO-W - RVO:68081766
    UT WOS000439956400010
    EID SCOPUS85048574353
    DOI10.1016/j.virol.2018.05.023
    AnotaceMurine cytomegalovirus (MCMV) has been reported from house mice (Mus musculus) worldwide, but only recently from Eastern house mice (M. m. musculus), of particular interest because they form a semi-permeable species barrier in Europe with Western house mice, M. in. domesticus. Here we report genome sequences of EastMCMV (from Eastern mice), and set these in the context of MCMV genomes from genus Mus hosts. We show EastMCMV and WestMCMV are genetically distinct. Phylogeny splitting analyses show a genome wide (94%) pattern consistent with no West-East introgression, the major exception (3.8%) being a genome-terminal region of duplicated genes involved in host immune system evasion. As expected from its function, this is a region of maintenance of ancestral polymorphism: The lack of clear splitting signal cannot be interpreted as evidence of introgression. The EastMCMV genome sequences reported here can therefore serve as a well-described resource for exploration of murid MCMV diversity.
    PracovištěÚstav biologie obratlovců
    KontaktHana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524
    Rok sběru2019
Počet záznamů: 1  

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