Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases

MISEHE, Mbilo, MATOUŠOVÁ, Marika, DVOŘÁKOVÁ, Alexandra, HERCÍK, Kamil, ŠKACH, Kryštof, CHALUPSKÁ, Dominika, DEJMEK, Milan, ŠÁLA, Michal, HÁJEK, Miroslav, BOUŘA, Evžen, MERTLÍKOVÁ-KAISEROVÁ, Helena, NENCKA, Radim. Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases. European Journal of Medicinal Chemistry. 2023, 260(November), 115717. ISSN 0223-5234. E-ISSN 1768-3254. Dostupné z: doi: 10.1016/j.ejmech.2023.115717.