Počet záznamů: 1  

Possible effects of the MC4R Asp298Asn polymorphism on pig production traits under ad libitum versus restricted feeding

  1. 1.
    0569355 - ÚŽFG 2024 RIV DE eng J - Článek v odborném periodiku
    Calta, J. - Zadinová, K. - Čítek, J. - Kluzáková, E. - Okrouhlá, M. - Stupka, R. - Tichý, L. - Machová, K. - Stratil, Antonín - Vostrý, L.
    Possible effects of the MC4R Asp298Asn polymorphism on pig production traits under ad libitum versus restricted feeding.
    Journal of Animal Breeding and Genetics. Roč. 140, č. 2 (2023), s. 207-215. ISSN 0931-2668. E-ISSN 1439-0388
    Institucionální podpora: RVO:67985904
    Klíčová slova: melanocortin 4 receptor * single nucleotide polymorphism * porcine production traits * feeding strategy
    Obor OECD: Genetics and heredity (medical genetics to be 3)
    Impakt faktor: 2.6, rok: 2022
    Způsob publikování: Omezený přístup
    https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=6473188838

    The missense mutation Asp298Asn in the melanocortin 4 receptor (MC4R) is associated with daily gain or fatness in pigs (Sus scrofa domesticus). However, to the best of our knowledge, no study has directly compared the effects of the polymorphism between different feeding levels, even though diet plays a vital role in the swine industry. To explore possible differences, data from 439 mostly commercial hybrids fattened ad libitum and 119 commercial hybrids fattened with restricted feed ration were collected. The recorded traits were average daily gain (ADG), feed conversion ratio (FCR), carcass weight (CW), dressing percentage (DP), lean meat content (LM), backfat thickness (BFT), lean cuts weight, and meat quality parameters such as pH, temperature, drip loss, and CIELAB colour space. The general linear model revealed that the overall effect of MC4R was not statistically significant, but significant differences (p < 0.05) were found in ADG, FCR, CW, DP, LM, and BFT. In the ad libitum category, the AA genotype (298Asn/298Asn) tended to be the most favourable for growth-related traits, with the lowest LM, which is consistent with previous findings. In the restricted category, on the other hand, GA heterozygotes (298Asp/298Asn) achieved the best performance in terms of growth, whereas AA homozygotes showed the worst performance. Therefore, these results raise the possibility of an interaction between MC4R and the feeding level.
    Trvalý link: https://hdl.handle.net/11104/0341760

     
     
Počet záznamů: 1  

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