Carbocyclic nucleosides with norbornane pseudosugar moiety locked in North conformation

0369987 - ÚOCHB 2012 GR eng A - Abstrakt
Dejmek, Milan - Hřebabecký, Hubert - Šála, Michal - Nencka, Radim
Carbocyclic nucleosides with norbornane pseudosugar moiety locked in North conformation.
ESOC 2011. 17th European Symposium on Organic Chemistry. Crete: University of Crete, 2011. P2.121-P2.121.
[ESOC 2011. European Symposium on Organic Chemistry /17./. 10.07.2011-15.07.2011, Crete]
Grant CEP: GA MŠMT 1M0508
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: norbornane * conformationally locked nucleosides * carbocyclic nucleosides
Kód oboru RIV: CC - Organická chemie

We report on synthesis of novel carbocylic nucleosides/tides locked in the North conformation. In order to lock the North conformation, norbornane substituted with base at C-3 position and with hydroxymethyl group at the bridgehead (C-1) position was used as the pseudosugar moiety.
Trvalý link: http://hdl.handle.net/11104/0203915