Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II

BÍM, D., NAVRÁTIL, M., GUTTEN, O., KONVALINKA, J., KUTIL, Z., CULKA, M., NAVRÁTIL, V., ALEXANDROVA, A. N., BAŘINKA, C., RULÍŠEK, L. Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II. Journal of Physical Chemistry B. 2022, 126(1), 132-143. ISSN 1520-6106. E-ISSN 1520-5207. Dostupné z: doi: 10.1021/acs.jpcb.1c09240.