Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

JÍLKOVÁ, A., RUBEŠOVÁ, P., FANFRLÍK, J., FAJTOVÁ, P., ŘEZÁČOVÁ, P., BRYNDA, J., LEPŠÍK, M., MERTLÍKOVÁ-KAISEROVÁ, H., EMAL, C. D., RENSLO, A. R., ROUSH, W. R., HORN, M., CAFFREY, C. R., MAREŠ, M. Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors. ACS Infectious Diseases. 2021, 7(5), 1077-1088. ISSN 2373-8227. Dostupné z: doi: 10.1021/acsinfecdis.0c00501.