Počet záznamů: 1
G4Killer web application: a tool to design G-quadruplex mutations
- 1.0539893 - BFÚ 2021 RIV GB eng J - Článek v odborném periodiku
Brázda, Václav - Kolomaznik, J. - Mergny, Jean-Louis - Šťastný, J.
G4Killer web application: a tool to design G-quadruplex mutations.
Bioinformatics. Roč. 36, č. 10 (2020), s. 3246-3247. ISSN 1367-4803. E-ISSN 1460-2059
Grant CEP: GA ČR(CZ) GA18-15548S; GA MŠMT EF15_003/0000477
Institucionální podpora: RVO:68081707
Klíčová slova: G4Killer * web application * G-quadruplex mutations
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 6.937, rok: 2020
Způsob publikování: Open access
https://academic.oup.com/bioinformatics/article/36/10/3246/5716328
Motivation: G-quadruplexes (G4) are important regulatory non-B DNA structures with therapeutic potential. A tool for rational design of mutations leading to decreased propensity for G4 formation should be useful in studying G4 functions. Although tools exist for G4 prediction, no easily accessible tool for the rational design of G4 mutations has been available.
Trvalý link: http://hdl.handle.net/11104/0317588
Počet záznamů: 1