Počet záznamů: 1
Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage
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SYSNO ASEP 0532829 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Phytohormone cytokinin guides microtubule dynamics during cell progression from proliferative to differentiated stage Tvůrce(i) Montesinos, J. C. (AT)
Abuzeineh, A. (BE)
Kopf, A. (AT)
Juanes-Garcia, A. (AT)
Ötvös, K. (AT)
Petrášek, Jan (UEB-Q) RID, ORCID
Sixt, M. (AT)
Benková, E. (AT)Celkový počet autorů 8 Číslo článku e104238 Zdroj.dok. EMBO Journal. - : Wiley - ISSN 0261-4189
Roč. 39, č. 17 (2020)Poč.str. 22 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova cell differentiation ; cytokinin ; cytoskeleton ; microtubules ; microtubules dynamics Vědní obor RIV EB - Genetika a molekulární biologie Obor OECD Biochemical research methods CEP EF16_019/0000738 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Způsob publikování Open access Institucionální podpora UEB-Q - RVO:61389030 UT WOS 000548311800001 EID SCOPUS 85087860829 DOI 10.15252/embj.2019104238 Anotace Cell production and differentiation for the acquisition of specific functions are key features of living systems. The dynamic network of cellular microtubules provides the necessary platform to accommodate processes associated with the transition of cells through the individual phases of cytogenesis. Here, we show that the plant hormone cytokinin fine-tunes the activity of the microtubular cytoskeleton during cell differentiation and counteracts microtubular rearrangements driven by the hormone auxin. The endogenous upward gradient of cytokinin activity along the longitudinal growth axis in Arabidopsis thaliana roots correlates with robust rearrangements of the microtubule cytoskeleton in epidermal cells progressing from the proliferative to the differentiation stage. Controlled increases in cytokinin activity result in premature re-organization of the microtubule network from transversal to an oblique disposition in cells prior to their differentiation, whereas attenuated hormone perception delays cytoskeleton conversion into a configuration typical for differentiated cells. Intriguingly, cytokinin can interfere with microtubules also in animal cells, such as leukocytes, suggesting that a cytokinin-sensitive control pathway for the microtubular cytoskeleton may be at least partially conserved between plant and animal cells. Pracoviště Ústav experimentální botaniky Kontakt David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Rok sběru 2021 Elektronická adresa http://doi.org/10.15252/embj.2019104238
Počet záznamů: 1