Počet záznamů: 1
Hyaluronan biofilms reinforced with partially deacetylated chitin nanowhiskers: extraction, fabrication, in-vitro and antibacterial properties of advanced nanocomposites
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SYSNO ASEP 0522175 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Hyaluronan biofilms reinforced with partially deacetylated chitin nanowhiskers: extraction, fabrication, in-vitro and antibacterial properties of advanced nanocomposites Tvůrce(i) Abdelrahman, R. M. (CZ)
Abdel-Mohsen, A. M. (CZ)
Zboncak, M. (CZ)
Franková, J. (CZ)
Lepcio, P. (CZ)
Kobera, Libor (UMCH-V) RID, ORCID
Steinhart, Miloš (UMCH-V) RID
Pavliňák, D. (CZ)
Spotaz, Z. (CZ)
Sklenářévá, R. (CZ)
Brus, Jiří (UMCH-V) RID, ORCID
Jancar, J. (CZ)Číslo článku 115951 Zdroj.dok. Carbohydrate Polymers. - : Elsevier - ISSN 0144-8617
Roč. 235, 1 May (2020), s. 1-13Poč.str. 13 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova nanocomposite biofilm ; hyaluronan ; nanowhiskers Vědní obor RIV CD - Makromolekulární chemie Obor OECD Polymer science Způsob publikování Omezený přístup Institucionální podpora UMCH-V - RVO:61389013 UT WOS 000519044900018 EID SCOPUS 85079329785 DOI 10.1016/j.carbpol.2020.115951 Anotace Fabrication of nanocomposite biofilms with enhanced mechanical and antibacterial properties was successfully achieved from hyaluronan (HA) and partially deacetylated chitin nanowhiskers (ChNWs) by a casting-evaporation method. The hydrolysis process of chitin showed an important role in the dimensions, stability, and the crystallinity of extracted ChNWs in a time-dependent manner. The volume fraction of ChNWs nanofiller varying from (0.001 to 0.5) exhibited a great influence on the mechanical properties of the biofilms (young modulus, strength) was enhanced by the high load-bearing capacity of NWs compared with net HA film. The antibacterial activity of the nanocomposite biofilms exhibited significant bactericidal activity against different types of bacteria (−/+ gram). HA/ChNWs Nanocomposite biofilms did not show any toxicity against normal human dermal fibroblasts (NHDF) and human primary osteogenic sarcoma (Saos-2) cell lines. The new biofilms with unique properties like edibleness, environmental friendliness, high mechanical properties, antibacterial performance, and non-cytotoxicity that could be used in skin tissue regenerations, and drug delivery applications. Pracoviště Ústav makromolekulární chemie Kontakt Eva Čechová, cechova@imc.cas.cz ; Tel.: 296 809 358 Rok sběru 2021 Elektronická adresa https://www.sciencedirect.com/science/article/pii/S0144861720301259?via%3Dihub
Počet záznamů: 1