Počet záznamů: 1
Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy
- 1.
SYSNO ASEP 0521416 Druh ASEP M - Kapitola v monografii Zařazení RIV C - Kapitola v knize Název Using Polymers to Enhance the Carbon Nanomaterial Biointerface Tvůrce(i) Pramanik, Goutam (UOCHB-X) ORCID
Neburková, Jitka (UOCHB-X) RID, ORCID
Vaněk, Václav (UOCHB-X) RID, ORCID
Jani, Mona (UOCHB-X)
Kindermann, Marek (UOCHB-X)
Cígler, Petr (UOCHB-X) RID, ORCIDZdroj.dok. Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy. - Hoboken : Wiley, 2019 / Hui Y. Y. ; Chang H.-C. ; Dong H. ; Zhang X. - ISBN 978-1-119-37345-2 Rozsah stran s. 15-42 Poč.str. 28 s. Poč.str.knihy 376 Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. US - Spojené státy americké Klíč. slova biomedical applications ; carbon nanomaterials ; covalent modification ; DLVO theory ; noncovalent coating ; nucleic acids ; polymer functionalization ; stimuli‐responsive polymers Vědní obor RIV CD - Makromolekulární chemie Obor OECD Nano-materials (production and properties) CEP GA18-17071S GA ČR - Grantová agentura ČR EF16_019/0000729 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora UOCHB-X - RVO:61388963 DOI 10.1002/9781119373476.ch2 Anotace This chapter focuses on functionalization of carbon nanomaterials (CNMs) with polymers for biomedical applications. A classical theoretical approach based on Derjaguin‐Landau‐Verwey‐Overbeek (DLVO) theory is commonly used to predict the stability of a colloidal system. CNMs can be functionalized with polymers via two types of approaches: noncovalent coating and covalent modification. The physicochemical properties of CNMs are determined by their intrinsic nanostructure. The chapter discusses the effect of polymer functionalization on the spectral properties of various CNMs. Stimuli‐responsive polymers respond to their environment by changing their physical and/or chemical properties. Among stimuli‐responsive polymers, thermoresponsive polymers have been exploited most abundantly to modify carbon nanoparticles. The development of nonviral, nonimmunogenic, and biocompatible vectors for efficient intracellular transfection of nucleic acids (NAs) is one of the challenges facing future gene therapy approaches. The surface of the CNMs can be functionalized by covalent or noncovalent attachment of macromolecular layers to create reliable nonviral gene delivery vectors. Pracoviště Ústav organické chemie a biochemie Kontakt asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Jana Procházková, Tel.: 220 183 418 Rok sběru 2020
Počet záznamů: 1