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Application of adult mesenchymal stem cells in bone and vascular tissue engineering
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SYSNO ASEP 0499595 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Application of adult mesenchymal stem cells in bone and vascular tissue engineering Tvůrce(i) Trávníčková, Martina (FGU-C) RID, ORCID, SAI
Bačáková, Lucie (FGU-C) RID, ORCIDZdroj.dok. Physiological Research. - : Fyziologický ústav AV ČR, v. v. i. - ISSN 0862-8408
Roč. 67, č. 6 (2018), s. 831-850Poč.str. 20 s. Jazyk dok. eng - angličtina Země vyd. CZ - Česká republika Klíč. slova adult mesenchymal stem cells ; adipose-derived stem cells ; patient factors ; bone tissue engineering ; vascular tissue engineering Vědní obor RIV EI - Biotechnologie a bionika Obor OECD Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction) CEP LQ1604 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy NV15-33018A GA MZd - Ministerstvo zdravotnictví Institucionální podpora FGU-C - RVO:67985823 UT WOS 000453554300001 EID SCOPUS 85058873790 DOI 10.33549/physiolres.933820 Anotace Tissue engineering is a very promising field of regenerative medicine. Life expectancy has been increasing, and tissue replacement is increasingly needed in patients suffering from various degenerative disorders of the organs. The use of adult mesenchymal stem cells (e.g. from adipose tissue or from bone marrow) in tissue engineering seems to be a promising approach for tissue replacements. Clinical applications can make direct use of the large secretome of these cells, which can have a positive influence on other cells around. Another advantage of adult mesenchymal stem cells is the possibility to differentiate them into various mature cells via appropriate culture conditions (i.e. medium composition, biomaterial properties, and dynamic conditions). This review is focused on current and future ways to carry out tissue replacement of damaged bones and blood vessels, especially with the use of suitable adult mesenchymal stem cells as a potential source of differentiated mature cells that can later be used for tissue replacement. The advantages and disadvantages of different stem cell sources are discussed, with a main focus on adipose-derived stem cells. Patient factors that can influence later clinical applications are taken into account. Pracoviště Fyziologický ústav Kontakt Lucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400 Rok sběru 2019
Počet záznamů: 1