Počet záznamů: 1
The silymarin composition ... and why does it matter???
- 1.
SYSNO ASEP 0481180 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The silymarin composition ... and why does it matter??? Tvůrce(i) Chambers, Christopher S. (MBU-M) RID, ORCID
Holečková, Veronika (MBU-M)
Petrásková, Lucie (MBU-M) ORCID
Biedermann, David (MBU-M) RID, ORCID
Valentová, Kateřina (MBU-M) RID, ORCID
Buchta, M. (CZ)
Křen, Vladimír (MBU-M) RID, ORCIDZdroj.dok. Food Research International. - : Elsevier - ISSN 0963-9969
Roč. 100, OCT 2017 (2017), s. 339-353Poč.str. 15 s. Jazyk dok. eng - angličtina Země vyd. NL - Nizozemsko Klíč. slova Silymarin ; Flavonolignans ; Milk thistle Vědní obor RIV CE - Biochemie Obor OECD Biochemistry and molecular biology CEP GA15-03037S GA ČR - Grantová agentura ČR NV16-27317A GA MZd - Ministerstvo zdravotnictví LD15081 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy LD15082 GA MŠMT - Ministerstvo školství, mládeže a tělovýchovy Institucionální podpora MBU-M - RVO:61388971 UT WOS 000413388700004 DOI 10.1016/j.foodres.2017.07.017 Anotace The extract from milk thistle (Silybum mariamen (L.) Gaertn. (Asteraceae)), known as silymarin, contains a variety of flavonolignans and displays antioxidant, anti-inflammatory, immunomodulatory and hepatoprotective properties. As silybin is the main component of silymarin, the literature mainly focuses on this compound, ignoring all other components. This leads to problems in reproducibility of scientific results, as the exact composition of silymarin is often unknown and can vary to a certain degree depending on the processing, chemovariety of the plant used and climatic conditions during the plant growth. There are studies dealing with the analytical separation and quantification of silymarin components as well as studies focused on silymarin content in clinically used drugs, in various plant parts, seasons, geographic locations etc. However, no comparison of detail flavonolignan profiles in various silymarin preparations is available to date. Also, as a result of the focus on the flavonolignans, the oil fraction, which contains linoleic, oleic and palmitic acids, sterols, tocopherol (vitamin E) and phospholipids, has been neglected. Due to all these factors, the whole plant is used e.g. as animal feed, the leaves can be eaten in salads and seed oil, besides culinary uses, can be also utilized for biodiesel or polymer production. Various HPLC separation techniques for the determination of the content of the flavonolignans have been vastly summarized in the present review. Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2018
Počet záznamů: 1