Počet záznamů: 1
Cell-based Tolerogenic Therapy, Experience from Animal Models of Multiple Sclerosis, Type 1 Diabetes and Rheumatoid Arthritis
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SYSNO ASEP 0477084 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Cell-based Tolerogenic Therapy, Experience from Animal Models of Multiple Sclerosis, Type 1 Diabetes and Rheumatoid Arthritis Tvůrce(i) Stojanovic, I. (RS)
Dimitrijevic, M. (RS)
Vives-Pi, M. (ES)
Mansilla, M.J. (ES)
Pujol-Autonell, I. (ES)
Rodriguez-Fernandez, S. (ES)
Pálová-Jelínková, L. (CZ)
Funda, David P. (MBU-M) RID, ORCID
Gruden-Movsesijan, A. (RS)
Sofronic-Milosavljevic, L. (RS)
Hilkens, C.M.U. (RS)
Martínez-Cáceres, E. (ES)
Miljković, D. (RS)Zdroj.dok. Current Pharmaceutical Design - ISSN 1381-6128
Roč. 23, č. 18 (2017), s. 2623-2643Poč.str. 21 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova Cell-based tolerogenic therapy ; regulatory T cells ; tolerogenic dendritic cells Vědní obor RIV EE - Mikrobiologie, virologie Obor OECD Microbiology CEP GA15-24487S GA ČR - Grantová agentura ČR Institucionální podpora MBU-M - RVO:61388971 UT WOS 000405678800007 EID SCOPUS 85025164921 DOI 10.2174/1381612823666170214120708 Anotace Cell-based tolerogenic therapy is a promising approach for the treatment of autoimmune diseases and transplant rejection. Regulatory T cells and tolerogenic dendritic cells have been particularly explored in the treatment of various autoimmune disorders in experimental models of disease. Although some of these cells have already been tested in a limited number of clinical trials, there is still a need for preclinical research on tolerogenic cells in animal models of autoimmunity. This review will focus on the relevance of data obtained from studies in experimental animal models for the use of tolerogenic cell-based therapy in humans. Also, perspectives for further improvement of tolerogenic cell preparation towards enhanced suppressive activity and stability of the cells will be discussed. Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2018
Počet záznamů: 1