Počet záznamů: 1
The structure and material composition of ossified aortic valves identified using a set of scientific methods
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SYSNO ASEP 0397509 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název The structure and material composition of ossified aortic valves identified using a set of scientific methods Tvůrce(i) Zeman, Antonín (UTAM-F) RID, SAI
Šmíd, M. (CZ)
Havelcová, Martina (USMH-B) RID, ORCID
Coufalová, L. (CZ)
Kučková, S. (CZ)
Velčovská, M. (CZ)
Hynek, R. (CZ)Celkový počet autorů 7 Zdroj.dok. Journal of Asian Earth Sciences. - : Elsevier - ISSN 1367-9120
Roč. 77, November (2013), s. 311-317Poč.str. 7 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova aortic stenosis ; degenerative (calcification–sclerotic) changes ; hydroxyapatite ; proteins ; cholesterol Vědní obor RIV DB - Geologie a mineralogie Institucionální podpora UTAM-F - RVO:68378297 ; USMH-B - RVO:67985891 UT WOS 000326996800030 EID SCOPUS 84885476900 DOI 10.1016/j.jseaes.2013.07.001 Anotace Degenerative aortic stenosis has become a common and dangerous disease in recent decades. This disease leads to the mineralization of aortic valves, their gradual thickening and loss of functionality. We studied the detailed assessment of the proportion and composition of inorganic and organic components in the ossified aortic valve, using a set of analytical methods applied in science: polarized light microscopy, scanning electron microscopy, X-ray fluorescence, X-ray diffraction, gas chromatography/mass spectrometry and liquid chromatography–tandem mass spectrometry. The sample valves showed the occurrence of phosphorus and calcium in the form of phosphate and calcium carbonate, hydroxyapatite, fluorapatite and hydroxy-fluorapatite, with varying content of inorganic components from 65 to 90 wt%, and with phased development of degenerative disability. The outer layers of the plaque contained an organic component with peptide bonds, fatty acids, proteins and cholesterol. Pracoviště Ústav teoretické a aplikované mechaniky Kontakt Kulawiecová Kateřina, kulawiecova@itam.cas.cz, Tel.: 225 443 285 Rok sběru 2014 Elektronická adresa http://www.sciencedirect.com/science/journal/13679120/77
Počet záznamů: 1