Determination of mefolinate, a metabolite of folic acid, in serum, blood and urine by capillary zone electrophoresis with isotachophoretic sample clean-up

0348770 - ÚIACH 2011 BE eng A - Abstrakt
Křivánková, Ludmila - Pantůčková, Pavla
Determination of mefolinate, a metabolite of folic acid, in serum, blood and urine by capillary zone electrophoresis with isotachophoretic sample clean-up.
Abstract Book. 34th ISCC and 7th GCxGC Symposium. Kortrijk: I.O.P.M.S. vzw, 2010 - (Sandra, T.; Sandra, P.). s. 227
[International Symposium on Capillary Chromatography /34./ and GCxGC Symposium /7./. 30.05.2010-04.06.2010, Riva del Garda]
Grant CEP: GA ČR GA203/08/1536; GA AV ČR IAA400310703
Výzkumný záměr: CEZ:AV0Z40310501
Klíčová slova: mefolinate * isotachophoresis * electrophoresis
Kód oboru RIV: CB - Analytická chemie, separace

Mefolinate (5-methyltetrahydrofolate) is the predominant circulating folate coenzyme in serum and its quantitative determination is one of several factors used in the diagnosis of folate deficiency. We have developed a new electrophoretic method for the determination of mefolinate in complex matrices of serum, whole blood and urine using the CS Isotachophoretic Analyzer EA 100 Villa Labeco with a column switching system.
Trvalý link: http://hdl.handle.net/11104/0189204