Počet záznamů: 1  

Fos expression in spinothalamic and postsynaptic dorsal column neurons following noxious visceral and cutaneous stimuli

  1. 1.
    SYSNO ASEP0142477
    Druh ASEPJ - Článek v odborném periodiku
    Zařazení RIVJ - Článek v odborném periodiku
    Poddruh JOstatní články
    NázevFos expression in spinothalamic and postsynaptic dorsal column neurons following noxious visceral and cutaneous stimuli
    Tvůrce(i) Paleček, Jiří (FGU-C) RID, ORCID
    Palečková, V. (US)
    Willis, W. D. (US)
    Zdroj.dok.Pain. - : Lippincott Williams & Wilkins - ISSN 0304-3959
    Roč. 104, 1-2 (2003), s. 249-257
    Poč.str.9 s.
    Jazyk dok.eng - angličtina
    Země vyd.NL - Nizozemsko
    Klíč. slovavisceral pain ; myelotomy ; postsynaptic dorsal column
    Vědní obor RIVFH - Neurologie, neurochirurgie, neurovědy
    CEPGA309/03/0752 GA ČR - Grantová agentura ČR
    CEZAV0Z5011922 - FGU-C
    AnotaceFos protein expression in retrogradely labeled spinothalamic tract (STT) and postsynaptic dorsal column (PSDC) neurons in the lumbosacral enlargement in rats was used as an anatomical marker of enhanced activation to compare the role of these neurons in cutaneous and visceral pain. The noxious stimuli used were intradermal injection of capsaicin and distention of the ureter. Retrogradely labeled neurons were found in laminae III-IV and in the vicinity of the central canal. STT neurons were located in laminae I, III-VII and X. Ureter distention evoked Fos expression in PSDC and STT neurons located in all laminae in which retrogradely labeled cell were found, with the maximum in the L2 spinal segment. The Fos-positive PSDC neurons represented a significantly higher percentage of the retrogradely labeled neurons than of the STT Fos-positive neurons. Intradermal capsaicin injection also evoked Fos expression in both PSDC and STT neurons, but with no significant difference between these two. These results show that both PSDC and STT neurons are activated by cutaneous and visceral noxious stimuli.
    PracovištěFyziologický ústav
    KontaktLucie Trajhanová, lucie.trajhanova@fgu.cas.cz, Tel.: 241 062 400
    Rok sběru2004

Počet záznamů: 1  

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