Metal Exchange Reactions in Metallothioneins Explored by Electrochemical Methods

0510095 - ÚFCH JH 2020 RIV DE eng J - Článek v odborném periodiku
Šestáková, Ivana - Navrátil, Tomáš - Josypčuk, Bohdan
Metal Exchange Reactions in Metallothioneins Explored by Electrochemical Methods.
Electroanalysis. Roč. 2019, č. 10 (2019), s. 2020-2023. ISSN 1040-0397. E-ISSN 1521-4109
Grant CEP: GA ČR GA17-03868S
Institucionální podpora: RVO:61388955
Klíčová slova: voltammetric determination * mercury * carbon * chronopotentiometry * phytochelatins * complexation * electrodes * cadmium * domain * cd * Metallothioneins
Obor OECD: Physical chemistry
Impakt faktor: 2.544, rok: 2019
Způsob publikování: Omezený přístup

Metallothioneins (MTs) are widely occurring, small, cysteine-rich proteins, important for essential metal (Zn, Cu) homeostasis and transport and for heavy metal (Cd, Hg) detoxification. In buffered solutions of mammalian MT, voltammetry and potentiometric striping analysis (PSA) can distinguish different coordination of bound metals or follow their exchange, especially that of zinc and cadmium for copper, silver, and cobalt. The examples of different electrode applications as of hanging mercury drop electrode (HMDE), of silver solid amalgam (AgSAE) electrode, and of silica gel modified carbon paste electrode (SiO2-CPE) are given.
Trvalý link: http://hdl.handle.net/11104/0300650