Počet záznamů: 1
Arabidopsis WAT1 is a vacuolar auxin transport facilitator required for auxin homoeostasis
- 1.0421943 - ÚEB 2014 RIV GB eng J - Článek v odborném periodiku
Ranocha, P. - Dima, O. - Nagy, R. - Novák, Ondřej - Goffner, D. … celkem 18 autorů
Arabidopsis WAT1 is a vacuolar auxin transport facilitator required for auxin homoeostasis.
Nature Communications. Roč. 4, č. 2013 (2013). E-ISSN 2041-1723
Grant CEP: GA MŠMT LK21306
Výzkumný záměr: CEZ:AV0Z50380511
Klíčová slova: BINDING PROTEIN-1 * POLAR TRANSPORT * PLANTS
Kód oboru RIV: EF - Botanika
Impakt faktor: 10.742, rok: 2013
The plant hormone auxin (indole-3-acetic acid, IAA) has a crucial role in plant development. Its spatiotemporal distribution is controlled by a combination of biosynthetic, metabolic and transport mechanisms. Four families of auxin transporters have been identified that mediate transport across the plasma or endoplasmic reticulum membrane. Here we report the discovery and the functional characterization of the first vacuolar auxin transporter. We demonstrate that WALLS ARE THIN1 (WAT1), a plant-specific protein that dictates secondary cell wall thickness of wood fibres, facilitates auxin export from isolated Arabidopsis vacuoles in yeast and in Xenopus oocytes. We unambiguously identify IAA and related metabolites in isolated Arabidopsis vacuoles, suggesting a key role for the vacuole in intracellular auxin homoeostasis. Moreover, local auxin application onto wat1 mutant stems restores fibre cell wall thickness. Our study provides new insight into the complexity of auxin transport in plants and a means to dissect auxin function during fibre differentiation.
Trvalý link: http://hdl.handle.net/11104/0228211
Název souboru Staženo Velikost Komentář Verze Přístup 2013_Ranocha_NATURE COMMUNICATIONS_2625.pdf 0 1.2 MB Jiná povolen
Počet záznamů: 1