Počet záznamů: 1
Deferoxamine derivatives as medicaments
- 1.0557146 - BTÚ 2022 RIV eng P - Patentový dokument
Truksa, Jaroslav - Werner, Lukáš - Štursa, Jan
Deferoxamine derivatives as medicaments.
2021. Vlastník: BIOTECHNOLOGICKÝ ÚSTAV AV ČR, v. v. i. SMART BRAIN, s.r.o. Datum udělení patentu: 25.08.2021. Číslo patentu: EP 3655414
Institucionální podpora: RVO:86652036
Klíčová slova: Iron * Cancer * Mitochondria
Obor OECD: Biochemistry and molecular biology
https://worldwide.espacenet.com/patent/search/family/059363022/publication/EP3655414B1?q=pn%3DEP3655414B1
The deferoxamine derivatives of general formula I and pharmaceutically acceptable salts thereof, at least one of R1 and R2 is a substituent of formula II. The novel derivatives are particularly suitable as medicaments, preferably for the treatment of cancer. Pharmaceutical preparations of compounds of formula I and a metal, preferably gallium, are also provided resulting in even more active medicaments or contrast agents. Combinations with other agents, resulting in synergistic effects are provided.
Trvalý link: http://hdl.handle.net/11104/0331200
Počet záznamů: 1