Extracellular polysaccharide produced by Chlorella vulgaris - Chemical characterization and anti-asthmatic profile

0517850 - MBÚ 2020 RIV NL eng J - Článek v odborném periodiku
Barboríková, J. - Šutovská, M. - Kazimierová, I. - Jošková, M. - Frantová, S. - Kopecký, Jiří - Čapek, P.
Extracellular polysaccharide produced by Chlorella vulgaris - Chemical characterization and anti-asthmatic profile.
International Journal of Biological Macromolecules. Roč. 135, AUG 15 2019 (2019), s. 1-11. ISSN 0141-8130. E-ISSN 1879-0003
Institucionální podpora: RVO:61388971
Klíčová slova: Green microalgae * Extracellular polysaccharide * Anti-asthmatic effect
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 5.162, rok: 2019
Způsob publikování: Omezený přístup
https://www.jbc.org/content/294/29/11131

Microalgae are the lowest plant organisms producing a wide range of metabolites that make them interesting organisms for industrial applications. Cultivation of green microalgal species Chlorella vulgaris resulted a significant production of extracellular polysaccharide (EPS). Preliminary chemico-spectroscopic studies on EPS revealed its molecular profile, a complex primary structure consisting of six monosaccharide units occurring in both furano and pyrano forms, a high sugar binding variability and the presence of partially methylated derivatives of some sugar constituents. Biological activity tests showed that EPS caused significant bronchodilatory, anti-inflammatory and antitussive effects in test animals. Chlorella EPS appears to be a promising agent for the prevention of chronic airway inflammation, which is the basic pathogenic mechanism of many respiratory diseases, including bronchial asthma.
Trvalý link: http://hdl.handle.net/11104/0303103