Preliminary study of Ge-DLC nanocomposite biomaterials prepared by laser codeposition

0505381 - FZÚ 2020 RIV CH eng J - Článek v odborném periodiku
Jelínek, Miroslav - Kocourek, Tomáš - Jurek, Karel - Jelínek, M. - Smolková, Barbora - Uzhytchak, Mariia - Lunov, Oleg
Preliminary study of Ge-DLC nanocomposite biomaterials prepared by laser codeposition.
Nanomaterials. Roč. 9, č. 3 (2019), s. 1-15, č. článku 451. E-ISSN 2079-4991
Grant CEP: GA MŠMT EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: germanium * DLC * doped biomaterials * pulsed laser deposition * reactive oxygen species * apoptosis * cytotoxicity
Obor OECD: Optics (including laser optics and quantum optics)
Impakt faktor: 4.324, rok: 2019
Způsob publikování: Open access

This paper deals with the synthesis and study of the properties of germanium-doped diamond-like carbon (DLC) films. For deposition of doped DLC films, hybrid laser technology was used. Using two deposition lasers, it was possible to arrange the dopant concentrations by varying the laser repetition rate. Doped films of Ge concentrations from 0 at.% to 12 at.% were prepared on Si (100) and fused silica (FS) substrates at room temperature. Film properties, such as growth rate, roughness, scanning electron microscopy (SEM) morphology, wavelength dependent X-ray spectroscopy (WDS) composition, VIS-near infrared (IR) transmittance, and biological properties (cytotoxicity, effects on cellular morphology, and ability to produce reactive oxygen species (ROS))were studied in relation to codeposition conditions and dopant concentrations. The analysis showed that Ge-DLC films exhibit cytotoxicity for higher Ge doping.
Trvalý link: http://hdl.handle.net/11104/0296823