Chemico-physical and pharmacodynamic properties of extracellular Dictyosphaerium chlorelloides biopolymer

0493063 - BÚ 2019 RIV GB eng J - Článek v odborném periodiku
Halaj, M. - Matulová, M. - Šutovská, M. - Barboríková, J. - Kazimierová, I. - Fraňová, S. - Přibyl, Pavel - Cepák, Vladislav - Lukavský, Jaromír - Capek, P.
Chemico-physical and pharmacodynamic properties of extracellular Dictyosphaerium chlorelloides biopolymer.
Carbohydrate Polymers. Roč. 198, OCT 15 2018 (2018), s. 215-224. ISSN 0144-8617. E-ISSN 1879-1344
Grant CEP: GA TA ČR TE01020080
Institucionální podpora: RVO:67985939
Klíčová slova: Biopolymer * Green microalgae * O-methylated galactoses
Obor OECD: Polymer science
Impakt faktor: 6.044, rok: 2018

Green microalga Dictyosphaerium chlorelloides was found to be a significant producer of the extracellular biopolymer, a potential fytochemical with pharmacodynamic properties. Dominant components of the biopolymer were found to be Gal (39 wt%) with its methyl derivatives (15 wt%), Rha (19 wt%) and Man (14 wt%). NMR spectroscopy revealed complex structure with galactan backbone branched by sugars in furano and pyrano forms in alpha and beta configurations. Biopolymer antitussive effect was similar to that of centrally acting antitussive drugs, indicating its relatively good antitussive potential.
Trvalý link: http://hdl.handle.net/11104/0286522