MRI-guided thermoablation of tumors in vivo using ferromagnetic nanoparticles

0399436 - FZÚ 2014 FR eng A - Abstrakt
Herynek, V. - Jendelová, Pavla - Turnovcová, Karolína - Pollert, Emil - Veverka, Miroslav - Veverka, Pavel - Jirák, D. - Syková, Eva - Hájek, M.
MRI-guided thermoablation of tumors in vivo using ferromagnetic nanoparticles.
Book of Abstracts. 30th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology. Toulouse: ESMRMB Organizing Commitee, 2013.
[Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology /30./. 03.10.2013-05.10.2013, Toulouse]
Grant CEP: GA MPO FR-TI3/521
Institucionální podpora: RVO:68378271 ; RVO:68378041
Klíčová slova: ferromagnetic nanoparticles * MRI * magnetic fluid hyperthermia * tumor thermoablation
Kód oboru RIV: BO - Biofyzika

heranostic ferromagnetic nanoparticles with low Curie temperature and high relaxivity represent a suitable agent for MRI-guided magnetic fluid hyperthermia applicable for tumor treatment. The nanoparticles deposited in the tissue may be heated by exposition to a high frequency (HF) electromagnetic field inducing apoptosis in their vicinity. The aim of our study was to verify the possibility of tumor thermoablation using the ferromagnetic particles in an animal experiment in vivo.
Trvalý link: http://hdl.handle.net/11104/0226719