Počet záznamů: 1
Acrosin inhibitor detection along epididymis
- 1.0388725 - BTÚ 2013 CZ eng A - Abstrakt
Davidová, Nina - Dorosh, Andriy - Jonáková, Věra - Postlerová, Pavla
Acrosin inhibitor detection along epididymis.
Book of abstract. Praha: Biotechnologický ústav v. v. i. AVČR, 2010 - (Pěknicová, J.). s. 67-67
[XVI. symposium českých reprodukčních imunologů s mezinárodní účastí. 28.05.2010-30.05.2010, Žďár nad Sázavou]
Grant CEP: GA MŠMT(CZ) 1M06011; GA ČR(CZ) GA303/09/1285; GA ČR(CZ) GA523/08/H064
Výzkumný záměr: CEZ:AV0Z50520701
Klíčová slova: Acrosin inhibitor * Epididymis * Substrate zymography
Kód oboru RIV: CE - Biochemie
We registered the increasing signal of acrosin inhibitor (AI) from caput to cauda epididymis. Gene expression of AI increased gradually throughout the epididymal duct, from its entry to the tail. Using specific antibody, AI was localized in the secretory tissues of caput, corpus and cauda epididymis by immunofluorescence. Proteinases and their inhibitors in reproductive fluids may play a significant role in reproduction processes. AI in the reproductive tract inactivates prematurely released sperm acrosin and protects spermatozoa and reproductive epithelium against proteolytic degradation.
Trvalý link: http://hdl.handle.net/11104/0218089
Počet záznamů: 1