Method of making arranged cell structures

0375168 - FZÚ 2012 RIV eng P - Patentový dokument
Rezek, Bohuslav - Michalíková, L. - Kromka, Alexander - Kalbáčová, M. - Kmoch, S. - Grausová, Ľubica - Bačáková, Lucie - Vaněček, Milan - Kočka, Jan
Method of making arranged cell structures.
2011. Vlastník: Fyzikální ústav AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. - Univerzita Karlova. Datum udělení patentu: 28.12.2011. Číslo patentu: EP2288699
Grant CEP: GA AV ČR KAN400100701; GA MŠMT LC510; GA AV ČR(CZ) IAAX00100902
Výzkumný záměr: CEZ:AV0Z10100521; CEZ:AV0Z50110509
Klíčová slova: biology * diamond * cell arrays * biomaterials * biointerfaces * bioelectronics
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus
https://data.epo.org/publication-server/pdf-document?pn=2288699&ki=B1&cc=EP

Way of fabricating ordered cell structures is specific by the procedure that hydrogen- and oxygen- terminated regions are generated on a diamond surface by plasma discharge and such diamond is immersed into the medium containing human-like cells. The cells, that are able to create bone or neuronal tissue, selectively colonize oxygen-terminated (hydrophilic) diamond surface. Crucial parameter is initial concentration of cells and of fetal bovine serum in the medium. Diamond can be also morphologically structured. Diamond can be natural or synthetic on arbitrary substrate. Concentration of dopants in diamond is not limited.
Trvalý link: http://hdl.handle.net/11104/0207900