Počet záznamů: 1
Cyanide inhibition and pyruvate-induced recovery of cytochrome c oxidase
- 1.0355550 - FGÚ 2011 RIV US eng J - Článek v odborném periodiku
Nůsková, Hana - Vrbacký, Marek - Drahota, Zdeněk - Houštěk, Josef
Cyanide inhibition and pyruvate-induced recovery of cytochrome c oxidase.
Journal of Bioenergetics and Biomembranes. Roč. 42, č. 5 (2010), s. 395-403. ISSN 0145-479X. E-ISSN 1573-6881
Grant CEP: GA ČR(CZ) GA303/07/0781; GA MŠMT(CZ) 1M0520; GA MŠMT OC08017
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: cytochrom c oxidase * cyanide * oxygen affinity
Kód oboru RIV: CE - Biochemie
Impakt faktor: 3.637, rok: 2010
Analysis of the mechanism of cyanide inhibitory effect on the mitochondrial cytochrome c oxidase demonstrates that the inhibition of COX by cyanide is fully reversible but the potential of pyruvate as a cyanide poisoning antidote is limited. COX affinity for oxygen is the most sensitive indicator of cyanide toxic effects
Trvalý link: http://hdl.handle.net/11104/0194296
Počet záznamů: 1