Počet záznamů: 1
Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling
- 1.0351450 - ÚOCHB 2011 RIV GB eng J - Článek v odborném periodiku
Nencka, Radim - Sinnaeve, D. - Karalic, I. - Martins, J. C. - Calenbergh, Van S.
Synthesis of C-6-substituted uridine phosphonates through aerobic ligand-free Suzuki-Miyaura cross-coupling.
Organic & Biomolecular Chemistry. Roč. 8, č. 22 (2010), s. 5234-5246. ISSN 1477-0520. E-ISSN 1477-0539
Výzkumný záměr: CEZ:AV0Z40550506
Klíčová slova: ligand-free * Suzuki-Miyaura cross-coupling * phosphonate
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 3.451, rok: 2010
An efficient protocol for the construction of C-6-(hetero)aryl-substituted uridine phosphonate analogues utilizing an aerobic, ligand-free Suzuki–Miyaura cross-coupling reaction of a 6-iodo-precursor in aqueous media has been established. The method presents a modular approach toward the target compounds as demonstrated by the synthesis of a small library comprising 14 novel nucleoside phosphonates.
Trvalý link: http://hdl.handle.net/11104/0191204
Počet záznamů: 1