0162513 - UIACH-O 20033076 RIV DE eng J - Článek v odborném periodiku
Klepárník, Karel - Horký, M.
Detection of DNA fragmentation in a single apoptotic cardiomyocyte by electrophoresis on a microfluidic device.
Electrophoresis. Roč. 24, č. 21 (2003), s. 3778-3783. ISSN 0173-0835. E-ISSN 1522-2683
Grant CEP: GA ČR GA203/00/0772; GA ČR GA203/03/0515; GA AV ČR IBS4031209
Výzkumný záměr: CEZ:AV0Z4031919
Klíčová slova: apoptosis cardiomyocyte * DNA fragmentation
Kód oboru RIV: CB - Analytická chemie, separace
Impakt faktor: 4.040, rok: 2003

The detection of doxorubicin-induced apoptosis in individual cardiomyocytes was performed on a microfluidic device. The causal relation between the enhanced doxorubicin concentration and the extent of DNA fragmentation in a single cell was confirmed. The results show that the extent of DNA fragmentation is proportional to the time of a cell treatment.
Trvalý link: http://hdl.handle.net/11104/0059822