Electrochemical Analysis of a Novel Ferrocene Derivative as a Potential Antitumor Drug

0446670 - ÚCHP 2016 RIV GB eng J - Článek v odborném periodiku
Bartošík, M. - Koubková, L. - Karban, Jindřich - Červenková Šťastná, Lucie - Hodík, Tomáš - Lamač, Martin - Pinkas, Jiří - Hrstka, R.
Electrochemical Analysis of a Novel Ferrocene Derivative as a Potential Antitumor Drug.
Analyst. Roč. 140, č. 17 (2015), s. 5864-5867. ISSN 0003-2654. E-ISSN 1364-5528
Grant CEP: GA ČR(CZ) GAP207/12/2368
Institucionální podpora: RVO:67985858 ; RVO:61388955
Klíčová slova: electrochemical measurement * sample preparation * nuclear and cytoplasm fraction extraction
Kód oboru RIV: CA - Anorganická chemie; CF - Fyzikální chemie a teoretická chemie (UFCH-W)
Impakt faktor: 4.033, rok: 2015

Ferrocenes represent an interesting group of drugs with potential antitumor properties. Moreover, their electronic properties make them suitable for electrochemical studies. We determined an uptake of novel ferrocene derivative in low µM concentrations by selected cancer cell lines and showed its localization predominantly in cytoplasm, using glassy carbon electrodes.
Trvalý link: http://hdl.handle.net/11104/0251153