Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain

0429538 - ÚEB 2015 RIV US eng J - Článek v odborném periodiku
Kvasnica, Miroslav - Oklešťková, Jana - Bazgier, Václav - Rárová, Lucie - Berka, K. - Strnad, Miroslav
Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.
Steroids. Roč. 85, JUL 2014 (2014), s. 58-64. ISSN 0039-128X. E-ISSN 1878-5867
Grant CEP: GA MŠMT LK21306; GA MŠMT(CZ) LO1204
Grant ostatní: GA MŠk ED2.1.00/03.0058
Program: ED
Institucionální podpora: RVO:61389030
Klíčová slova: Anticancer activity * Brassinosteroids * Organic synthesis
Kód oboru RIV: EF - Botanika
Impakt faktor: 2.639, rok: 2014
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord&UT=000337652700008

Thirteen monohydroxylated brassinosteroids analogues were synthesized and tested for their biological activity in plant and animal systems. The cytotoxic activity of the products was studied using human normal and cancer cell lines with 28-homocastasterone as positive control, their brassinolide type activity was established using the bean second-internode test with 24-epibrassinolide as standard.
Trvalý link: http://hdl.handle.net/11104/0234630